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CAS RN: 624-49-7 | 產品號碼: F0069
Dimethyl Fumarate
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 103.0 to 105.0 °C |
性質
| 熔點 | 104 °C |
| 沸點 | 205 °C |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Acetone, Chloroform |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H312 : Harmful in contact with skin. H315 : Causes skin irritation. H318 : Causes serious eye damage. H317 : May cause an allergic skin reaction. H401 : Toxic to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
相關法規
| RTECS # | EM6125000 |
運輸資料
| HS編碼* | 2917.19-000 |
Application
Dimethyl Fumarate, An Immunomodulator without Significant Immunosuppression
Recently, the effects of dimethyl fumarate on neuroprotection and immunomodulation have reported. Dimethyl fumarate is thought to have immunomodulatory properties without significant immunosuppression. (The product is for research purpose only.)
References
- The antipsoriatic agent dimethylfumarate immunomodulates T-cell cytokine secretion and inhibits cytokines of the psoriatic cytokine network
- Dimethylfumarate is a potent inducer of apoptosis in human T cells
- Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
- Dimethylfumarate Induces Immunosuppression via Glutathione Depletion and Subsequent Induction of Heme Oxygenase 1
- Dimethyl fumarate for multiple sclerosis
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