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CAS RN: 56974-61-9 | 產品號碼: G0464
補充產品訊息:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
產品號碼 | G0464 |
純度/分析方法 ![]() |
>97.0%(N) |
分子式 / 分子量 | C__1__6H__2__3N__3O__4·CH__4O__3S = 417.48 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Room Temperature (Recommended in a cool and dark place, <15°C) |
包裝和容器 ![]() |
1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 56974-61-9 |
相關CAS RN ![]() |
39492-01-8 |
Reaxys-RN | 5702026 |
PubChem Substance ID | 253660880 |
Merck Index(14) | 4320 |
MDL編號 | MFCD00210299 |
產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 94.0 area% |
Purity(with Total Nitrogen) | min. 97.0 % |
Melting point | 89.0 to 93.0 °C |
性質
熔點 | 91 °C |
溶解性(可溶於) | Methanol |
溶解性(微溶於) | Acetone |
溶解性(不溶於) | Ether |
GHS
相關法規
RTECS # | DG2800800 |
運輸資料
HS編碼* | 2925.29-000 |
Application
Gabexate Mesylate: A Synthetic Non-Peptide Protease Inhibitor
Gabexate mesylate is a synthetic non-peptide protease inhibitor. It inhibits trypsin, kallikrein, thrombin, plasmin, C1 esterase, and etc. Gabexate mesylate inhibit thrombin and activated factor X, being independent of plasma antithrombin level. Gabexate mesylate is used as anticoagulants for the treatment of disseminated intravascular coagulation (DIC). (The product is for research purpose only.)
References
- FOY: [ethyl-p-(6-guanidinohexanoyloxy) benzoate] methanesulfonate as a serine proteinase inhibitor. I. Inhibition of thrombin and factor Xa in vitro
- Gabexate mesylate and pivmecillinam hydrochloride (a review)
- D. F. Weetman, Drugs Today 1978, 14, 411.
- Competitive inhibition of swine kidney copper amine oxidase by drugs: amiloride, clonidine, and gabexate mesylate
- Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-α producation by inhibiting activation of both nuclear factor-κB and activator protein-1 in human monocytes
- Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis
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