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CAS RN: 210353-53-0 | 產品號碼: G0617
Gemifloxacin Mesylate
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 10MG |
NT$4,998
|
8 | 20 | 下單後約2週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
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| 產品號碼 | G0617 |
純度/分析方法 
|
>95.0%(HPLC)(qNMR) |
| 分子式 / 分子量 | C__1__8H__2__0FN__5O__4·CH__4O__3S = 485.49 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 210353-53-0 |
| Reaxys-RN | 8887755 |
| MDL編號 | MFCD08277637 |
產品規格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
性質
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H317 : May cause an allergic skin reaction. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相關法規
| RTECS # | QN2790988 |
運輸資料
| HS編碼* | 2933.99-000 |
Application
Gemifloxacin Mesylate: An Orally Active Broad-Spectrum Respiratory Quinolone Antibiotic
Gemifloxacin mesylate (LB20304) is an orally active broad-spectrum fluoroquinolone antibiotic. Fluoroquinolones, including gemifloxacin, inhibit DNA synthesis by inhibiting DNA gyrase and topoisomerase IV activities.1-3) The newest fluoroquinolones, such as gemifloxacin, gatifloxacin [G0627] and moxifloxacin [M2479], are known to have excellent in vitro activity against a wide range of respiratory pathogens and many aerobic Gram-negative organisms.3) (The product is for research purpose only.)
References
- 1) Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl -6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)
- 2) Gemifloxacin (a review)
- 3) Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones (a review)
- 4) Reverse phase-HPLC and HPTLC methods for determination of gemifloxacin mesylate in human plasma
- 5) Determination of gemifloxacin in different tissues of rat after oral dosing of gemifloxacin mesylate by LC-MS/MS and its application in drug tissue distribution study
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