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CAS RN: 130495-35-1 | 產品號碼: K0066
SKF-96365
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| 產品號碼 | K0066 |
純度/分析方法
|
>98%(HPLC) |
| 分子式 / 分子量 | C__2__2H__2__6N__2O__3·HCl = 402.92 |
| 外觀與形狀(20°C) | Solid |
儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic |
包裝和容器
|
50MG-Glass Bottle with Plastic Insert (閲覽圖片) |
| CAS RN | 130495-35-1 |
| Reaxys-RN | 7402134 |
| PubChem Substance ID | 468592133 |
| MDL編號 | MFCD00236407 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
性質
| 熔點 | 119 °C |
GHS
相關法規
| RTECS # | NI6823500 |
運輸資料
| HS編碼* | 2933.29-000 |
Application
SKF-96365: An Inhibitor of Receptor-Mediated Calcium Entry, and a TRPC Channel Antagonist
SKF-96365 is first reported as an inhibitor of receptor-mediated calcium entry.1) But recently, SKF-96365 is also used as an antagonist (blocker) of transient receptor potential canonical type (TRPC) channels which represent important molecules involved in hormonal signal transduction.2,3)
References
- 1) SK&F 96365, a novel inhibitor of receptor-mediated calcium entry
- 2) The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels
- 3) Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels (a review)
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