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CAS RN: 88678-31-3 | 產品號碼: L0301
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 8.00 to 9.00 % |
| Melting point | 97.0 to 101.0 °C |
性質
| 熔點 | 99 °C |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Chloroform, Acetone, dichloromethane |
| 溶解性（微溶於） | Diethyl ether |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相關法規
| RTECS # | FD3890000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Liranaftate: A Synthetic Thiocarbamate Antifungal Reagent
Liranaftate (piritetrate or M-732) is a chemical synthetic antifungal reagent, belonging chemically to the thiocarbamates. Although the exact mechanism of action is not entirely known, liranaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane. Similar antifungal reagent includes tolnaftate [T3059]. (The product is for research purpose only.)
References
- Inhibitory effect of a new mycotic agent, piritetrate on ergosterol biosynthesis in pathogenic fungi
- In vitro and in vivo activities of piritetrate (M-732), a new antidermatophytic thiocarbamate
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