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CAS RN: 187164-19-8 | 產品號碼: L0306
| 產品號碼 | L0306 |
純度/分析方法 
|
>98.0%(HPLC)(N) |
| 分子式 / 分子量 | C__1__4H__9Cl__2N__3S__2 = 354.27 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 應避免的情況 | Light Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片）, 250MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 187164-19-8 |
| Reaxys-RN | 8994672 |
| PubChem Substance ID | 468592145 |
| MDL編號 | MFCD00953915 |
產品規格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 150.0 to 154.0 °C |
| Specific rotation [a]20/D | -48.0 to -53.0 deg(C=1, DMF) |
性質
| 熔點 | 152 °C |
| 比旋光 [α]D | -50° (C=1,DMF) |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Acetone |
| 溶解性（微溶於） | Methanol |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
運輸資料
| HS編碼* | 2934.99-000 |
Application
Lluliconazole: An Optically Active Imidazole Antifungal Agent with Broad-Spectrum Activity
Lluliconazole (NND-502), an optically active imidazole antifungal agent with broad-spectrum activity, appears to inhibit ergosterol synthesis of fungi by inhibiting the enzyme lanosterol 14 α-demethylase. Inhibition of this enzyme’s activity by lluliconazole results in decreased amounts of ergosterol, a constituent of fungal cell membranes. Especially, luliconazole inhibited growth of all filamentous fungi except zygomycetes at low concentration. In addition, luliconazole is the active R enantiomer of a chiral molecule. (The product is for research purpose only.)
References
- In vitro and in vivo antidermatophyte activities of NND-502, a novel optically active imidazole antimycotic agent
- Inhibition of sterol 14 α-demethylation of Candida albicans with NND-502, a novel optically active imidazole antimycotic agent
- Lanoconazole and its related optically active compound NND-502: Novel antifungal imidazoles with a ketene dithioacetal structure (a review)
- In vitro antifungal activities of luliconazole, a new topical imidazole
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