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CAS RN: 84371-65-3 | 產品號碼: M1732
| 產品號碼 | M1732 |
純度/分析方法
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__9H__3__5NO__2 = 429.60 |
| 外觀與形狀(20°C) | Solid |
儲存條件
|
Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
包裝和容器
|
1G-Glass Bottle with Plastic Insert (閲覽圖片) |
| CAS RN | 84371-65-3 |
| Reaxys-RN | 5779404 |
| PubChem Substance ID | 87558747 |
| Merck Index(14) | 6186 |
產品規格
| Appearance | White to Light yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 192.0 to 198.0 °C |
| Specific rotation [a]20/D | +138.0 to +144.0 deg(C=0.5, CHCl3) |
| NMR | confirm to structure |
性質
| 熔點 | 195 °C |
| 比旋光 [α]D | 141° (C=0.5,CHCl3) |
| 溶解性(可溶於) | Chloroform |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
相關法規
| RTECS # | KG2955000 |
運輸資料
| HS編碼* | 2937.29-000 |
Application
Bacterial spore germinant research
Bacterial spores are more resistant to antibiotics and nutritional deficiencies than their vegetative cells and sometimes cause serious problems from the viewpoint of hygiene in clinical treatment and food processing.1) Spore persistence also plays a major role in the recurrence of infections after antibiotic treatment. Molecules that stimulate germination are termed “germinants”1) and the efficacy of germinant administration combined with antibiotics have been evaluated (for example, reports by N. Budi et al.2,3)). Mifepristone has been reported to act as a germinant for Clostridium sordellii spores (EC50 = 6.3 μM) and as an inhibitor for Clostridium difficle spores (IC50 = 18.2 μM).4)
(The product is for research purpose only.)
(The product is for research purpose only.)
References
- 1) Germinants and Their Receptors in Clostridia
- 2) Omadacycline Compared to Vancomycin When Combined with Germinants To Disrupt the Life Cycle of Clostridioides difficile.
- 3) Efficacy of Omadacycline or Vancomycin Combined With Germinants for Preventing Clostridioides difficile Relapse in a Murine Model
- 4) Progesterone Analogs Influence Germination of Clostridium sordellii and Clostriduim difficile Spores In Vitro
PubMed Literature

