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CAS RN: 71125-38-7 | 產品號碼: M1959
產品規格
| Appearance | White to Light yellow to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 96.0 % |
性質
| 熔點 | 255 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 : Toxic if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | DL0702000 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2935.90-000 |
Application
Meloxicam: A Preferential Cyclooxygenase-2 (COX-2) Inhibitor
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID), and a preferential cyclooxygenase-2 (COX-2) inhibitor. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. In theory, a drug that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1. (The product is for research purpose only.)
References
- Meloxican: Influence on arachidonic acid metabolism: Part 1. In vitro findings
- Meloxican: Influence on arachidonic acid metabolism: Part II. In vivo findings
- Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1
- Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4’-isomer
- Meloxicam: a reappraisal of pharmacokinetics, efficacy and safety (a review)
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