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CAS RN: 1722-62-9 | 產品號碼: M2560
Mepivacaine Hydrochloride
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
性質
| 熔點 | 263 °C |
| 水溶性 | Soluble |
| 溶解性（可溶於） | Methanol |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | TK6475000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Mepivacaine Hydrochloride: A Local Anesthetic of the Amide Type
Mepivacaine hydrochloride is a local anesthetic of the amide type which includes lidocain [L0156], mepivacaine hydrochloride [M2560], prilocaine hydrochloride [P2038], bupivacaine hydrochloride [B3925] and articaine. Mepivacaine is rapidly metabolized in liver, and is rapidly excreted via the kidneys. It has been reported that mepivacaine and procaine [P1961] have less toxicity than other local anesthetics.
References
- Pharmacokinetic and clinical pharmacological studies with mepivacaine and prilocaine (a review)
- Pharmacologic correlation between local anesthetic-induced myotoxicity and disturbances of intracellular calcium distribution (a review)
- Procaine and mepivacaine have less toxicity in vitro than other clinically used local anesthetics
- Efficacy and safety of mepivacaine compared with lidocaine in local anaesthesia in dentistry: a meta-analysis of randomised controlled trials
- Simultaneous determination of bupivacaine, mepivacaine, prilocaine and ropivacaine in human serum by liquid chromatography-tandem mass spectrometry
考研文獻
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