Maximum quantity allowed is 999
请选择数量
CAS RN: 12650-69-0 | 產品號碼: M2955
| 產品號碼 | M2955 |
純度/分析方法 
|
>98.0%(T) |
| 分子式 / 分子量 | C__2__6H__4__4O__9 = 500.63 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Frozen (<0°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Hygroscopic,Heat Sensitive |
| 包裝和容器
|
100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 25MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 12650-69-0 |
| Reaxys-RN | 4726470 |
| PubChem Substance ID | 354334600 |
| Merck Index(14) | 6302 |
| MDL編號 | MFCD01711620 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 92.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -18.0 to -21.0 deg(C=1,MeOH) |
| NMR | confirm to structure |
性質
| 熔點 | 78 °C |
| 比旋光 [α]D | -19° (C=1,MeOH) |
| Maximum Wavelength | 222 nm (EtOH) |
GHS
相關法規
| RTECS # | RA6907000 |
運輸資料
| HS編碼* | 2941.90-000 |
Application
RNA合成酵素を阻害する抗生物質，ムピロシン
Mupirocin is a polyketide antibiotic produced by fermentation using the organism Pseudomonas fluorescens. Mupirocin is fungicidally active against a wide range of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Mupirocin is also active against certain Gram-negative bacteria. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. Due to its mode of action, mupirocin does not demonstrate cross resistance with other classes of antibiotic agents. The calcium salt of mupirocin is used as an ointment to control the carriage of MRSA on skin and in nasal passages as well as for various skin infections. Recently, mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world. (The product is for research purpose only.)
References
- Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid
- Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use
- Mupirocin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use (a review)
- Insights into editing from an Ile-tRNA synthetase structure with tRNAIle and mupirocin
- Mupirocin resistance (a review)
- Resistance to and synthesis of the antibiotic mupirocin (a review)
- Development and validation of RP-HPLC method for simultaneous estimation of prednicarbate, mupirocin and ketoconazole in topical dosage forms
考研文獻
文檔
產品介紹報導
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）
SDS
請選擇語言。
請求的SDS不可用。
如需更多幫助，請聯繫我們 。
產品規格
檢驗報告(CoA)及其他文檔
請輸入批號
輸入的批號不正確
示例 CoA
可下載CoA示例。注：該示例可能非最新批次的CoA。
目前沒有該產品的 CoA 示例。
分析圖譜
請輸入批號
輸入的批號不正確
很抱歉，您搜索的分析圖譜無法提供。