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Product Document Searching Made Easy by 2D Code! | TCI Chemistry News July 2025 | [Product Highlights] Travoprost with Intra-Ocular-... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 21829-25-4 | 產品號碼: N0528
產品號碼 | N0528 |
純度/分析方法 ![]() |
>98.0%(E)(HPLC) |
分子式 / 分子量 | C__1__7H__1__8N__2O__6 = 346.34 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Room Temperature (Recommended in a cool and dark place, <15°C) |
應避免的情況 | Light Sensitive |
CAS RN | 21829-25-4 |
Reaxys-RN | 497773 |
PubChem Substance ID | 87573853 |
SDBS (AIST Spectral DB) | 9750 |
Merck Index(14) | 6528 |
MDL編號 | MFCD00057326 |
產品規格
Appearance | Light yellow to Yellow to Orange powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(UV-vis method) | min. 98.0 % |
Melting point | 172.0 to 175.0 °C |
Solubility in Acetone | almost transparency |
NMR | confirm to structure |
性質
熔點 | 174 °C |
溶解性(可溶於) | Chloroform, Acetone |
GHS
圖形表示 |
![]() |
信號詞 | Warning |
危險性說明 | H302 : Harmful if swallowed. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
RTECS # | US7975000 |
運輸資料
HS編碼* | 2933.39-000 |
Application
Type IV secretion system (T4SS) research
Reference
- Chemical Genetics Reveals Bacterial and Host Cell Functions Critical for Type IV Effector Translocation by Legionella pneumophila
Application
Nifedipine: A Short-Acting Dihydropyridine Calcium Antagonist
Nifedipine is a short-acting dihydropyridine calcium antagonist. It selectively inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle without altering serum calcium concentrations, and induces a relaxation of the muscle. Because of the dilation of resistance vessels, blood pressure falls. Nifedipine is almost completely metabolized by cytochrome P450 3A4 (CYP3A4) in the liver. Nifedipine is a poorly water soluble agent and rapidly metabolized resulting in decreased bioavailability, and then the short-acting can provide increased the risk of stroke et al. Therefore, nifedipine slow-release formulations have been developed. (The product is for research purpose only.)
References
- Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischemic heart disease, hypertension and related cardiovascular disorders
- Comparative pharmacology of calcium antagonists: nifedipine, verapamil [V0118] and diltiazem [D3662] (a review)
- Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine
- In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes P450: Role of CYP3A4 and CYP3A5
- Modified-release nifedipine: a review of the use of modified-release formulations in the treatment of hypertension and angina pectoris (a review)
- Analysis of nifedipine and its pyridine metabolite dehydronifedipine in blood and plasma: review and improved high-performance liquid chromatographic methodology
Application
Photobase Generator
References
- S. Song, S. Yokoyama, S. Takahara, T. Yamaoka, Polym. Adv. Technol. 1998, 9, 326.
- S. Song, S. Takahara, T. Yamaoka, J. Photopolym. Sci. Technol. 1998, 11, 171.
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