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CAS RN: 894-71-3 | 產品號碼: N0957
Nortriptyline Hydrochloride
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 5G |
NT$2,940
|
11 | 19 | 下單後約2週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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洽詢。
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| 產品號碼 | N0957 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__9H__2__1N·HCl = 299.84 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 應避免的情況 | Light Sensitive |
| CAS RN | 894-71-3 |
| 相關CAS RN
|
72-69-5 |
| Reaxys-RN | 4163872 |
| PubChem Substance ID | 253662334 |
| Merck Index(14) | 6715 |
| MDL編號 | MFCD00058024 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 216.0 to 220.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 218 °C |
| Maximum Wavelength | 237 nm (H__2O) |
| 水溶性 | Slightly soluble |
| 溶解性（可溶於） | Ethanol |
| 溶解性（不溶於） | Ether, Benzene, Acetone |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | HP0175000 |
運輸資料
| HS編碼* | 2921.49-000 |
Application
三環性抗うつ薬ノルトリプチリン
Nortriptyline hydrochloride is a tricyclic antidepressant. The mechanism of action is currently not clear, but it is assumed that nortriptyline inhibits the reuptake of noradrenaline [A0906] in brain. Nortriptyline is metabolized by P450 enzyme CYP2D6 into trans-10-hydroxynortriptyline which is reported as an active form. Recently, nortriptyline hydrochloride is mainly used for smoking cessation. (The product is for research purpose only.)
References
- Nortriptyline hydrochloride (a review of the physical properties of it)
- 10-hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes
- The Metabolic Fate of Amitriptyline, Nortriptyline and Amitriptylinoxide in Man (a review)
- Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach
- Nortriptyline for smoking cessation: A review
考研文獻
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