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CAS RN: 73590-85-9 | 產品號碼: O0437
Omeprazole Sulfide
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 122.0 to 126.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 124 °C |
| Maximum Wavelength | 307 nm (MeOH) |
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
オメプラゾール の合成中間体かつ代謝生成物，オメプラゾールスルフィド
Omeprazole sulfide is a synthetic intermediate and a metabolite of omeprazole [O0359]. In 2000s, asymmetric oxidation of omeprazole sulfide to esomeprazole, the active (S)-enantiomer of omeprazole, has been reported.
References
- Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide
- A simple and sensitive bioanalytical assay for simultaneous determination of omeprazole and its three major metabolites in human blood plasma using RP-HPLC after a simple liquid-liquid extraction procedure
- Asymmetric synthesis of esomeprazole
- Catalytic asymmetric oxidation of heteroaromatic sulfides with tert-butyl hydroperoxide catalyzed by a titanium complex with a new chiral 1,2-diphenylethane-1,2-diol ligand
- Tetra(tetraalkylammonium)octamolybdate catalysts for selective oxidation of sulfides to sulfoxides with hydrogen peroxide
- Asymmetric Oxidation Catalysis by a Porphyrin-Inspired Manganese Complex: Highly Enantioselective Sulfoxidation with a Wide Substrate Scope
PubMed Literature
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