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CAS RN: 68890-66-4 | 產品號碼: P2178
Piroctone Olamine
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| 產品號碼 | P2178 |
純度/分析方法 
|
>97.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__4H__2__3NO__2·C__2H__7NO = 298.43 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 68890-66-4 |
| 相關CAS RN
|
50650-76-5 |
| Reaxys-RN | 7503297 |
| PubChem Substance ID | 253662076 |
| Merck Index(14) | 7502 |
| MDL編號 | MFCD01690792 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 134.0 to 138.0 °C |
性質
| 熔點 | 136 °C |
| 溶解性（可溶於） | Methanol |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H315 : Causes skin irritation. H318 : Causes serious eye damage. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
相關法規
| RTECS # | UU7786150 |
運輸資料
| HS編碼* | 2933.79-000 |
Application
Piroctone olamine: A Hydroxypyridone Antimycotic
Piroctone olamine belongs to the class of hydroxypyridone antimycotics. The mode of action of hydroxypyridone antimycotics is not fully understood. It is often used as an antidandruff agent with shampoo and etc. (The product is for research purpose only.)
References
- Antidandruff hair tonic containing piroctone olamine
- E. Futterer, Cosmet. Toiletries 1988, 103, 49-50, 52.
- The antidandruff efficacy of a shampoo containing piroctone olamine and salicylic acid in comparison to that of a zinc phyrithione shampoo
- In vitro antimycotic activity and nail permeation models of a piroctone olamine (octopirox) containing transungual water soluble technology
- In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans
- Increased in vivo efficacy of lenalidomide by addition of piroctone olamine
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