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CAS RN: 23496-41-5 | 產品號碼: P2610
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Specific rotation [a]20/D | -18.0 to -23.0 deg(C=0.2, ethanol) |
| NMR | confirm to structure |
性質
| 熔點 | 223 °C |
| 比旋光 [α]D | -20° (C=0.2,EtOH) |
GHS
相關法規
運輸資料
| HS編碼* | 2939.79-000 |
Application
Peimine: A Bioactive Alkaloid with Antitussive, Expectorant and Anti-Inflammatory Activities
Peimine (verticine) and peiminine (verticinone) [P2609] are major active alkaloids isolated from the bulbs of Fritillaria ussuriensis, which is an Asian species of herbaceous plant in the lily family and a commonly used antitussive traditional Chinese medicinal (TCM) herb.1,2) It has been reported that peimine and peiminine also exhibit potent antitussive, expectorant and anti-inflammatory effects.3,4) In addition, peimine inhibits telomerase activity and thus may act as an antitumor agent.5) (The product is for research purpose only.)
References
- 1) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high-performance liquid chromatography coupled with evaporative light scattering detection
- 2) Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
- 3) Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae
- 4) Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level
- 5) Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves
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