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CAS RN: 6724-53-4 | 產品號碼: P3145
Perhexiline Maleate
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| 產品號碼 | P3145 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__9H__3__5N·C__4H__4O__4 = 393.57 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 6724-53-4 |
| Reaxys-RN | 6459396 |
| MDL編號 | MFCD00057329 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
GHS
相關法規
| RTECS # | TM7068000 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
Perhexiline Maleate: A Carnitine Palmitoyltransferase 1 (CPT1) and 2 (CPT2) Inhibitor
Perhexiline maleate is a carnitine palmitoyltransferase 1 (CPT1) and 2 (CPT2) inhibitor originally developed in the 1970s as an anti-anginal drug. CPT1/2 are mitochondrial enzymes responsible for the mitochondrial uptake of long chain fatty acids. Perhexiline maleate reduces fatty acid metabolism by inhibiting CPT1/2.1,2) Recently, perhexiline maleate has also received attention as an anticancer agent.3) (The product is for research use only.)
References
- 1) Systematic review of the efficacy and safety of perhexiline in the treatment of ischemic heart disease
- 2) Perhexiline (a review)
- 3) Perhexiline: Old Drug, New Tricks A Summary of Its Anti-Cancer Effects
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）
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