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CAS RN: 72559-06-9 | 產品號碼: R0211
產品號碼 | R0211 |
純度/分析方法 ![]() |
>98.0%(HPLC) |
分子式 / 分子量 | C__4__6H__6__2N__4O__1__1 = 847.02 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Frozen (<0°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 ![]() |
100MG-Glass Bottle with Plastic Insert (閲覽圖片), 1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 72559-06-9 |
Reaxys-RN | 3584778 |
PubChem Substance ID | 468592785 |
Merck Index(14) | 8213 |
MDL編號 | MFCD00866816 |
產品規格
Appearance | Red to Dark red to Dark purple powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 97.0 % |
性質
熔點 | 156 °C |
Maximum Wavelength | 493 nm (MeOH) |
溶解性(可溶於) | Methanol |
溶解性(微溶於) | Ethanol |
GHS
相關法規
RTECS # | VJ6700000 |
運輸資料
HS編碼* | 2941.90-000 |
Application
Rifabutin: a derivative of rifamycin S with anti-mycobacteria activity
Rifabutin is a derivative of rifamycin S [R0200], belonging to the class of ansamycins, with activity against mycobacteria including atypical organisms such as Mycobacterium avium and M. intracellulare, also referred to as Mycobacterium avium-intracellulare complex (MAC). Rifabutin inhibits DNA-dependent RNA polymerase in susceptible strains of Escherichia coli and Bacillus subtilis but not in mammalian cells. (The product is for research purpose only.)
References
- Rifabutin: a review of its antimicrobial activity, pharmacokinetic properties and therapeutic efficacy
- Rifamycin-Mode of Action, Resistance, and Biosynthesis (a review)
- Update on Rifampin and Rifabutin Drug Interactions
- Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography
- Identification of rat urinary metabolites of rifabutin using LC-MSn and LC-HR-MS
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