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CAS RN: 6106-46-3 | 產品號碼: S0230
Scopolamine Methyl Nitrate

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產品號碼 | S0230 |
純度/分析方法 ![]() |
>98.0%(T)(HPLC) |
分子式 / 分子量 | C__1__8H__2__4N__2O__7 = 380.40 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Room Temperature (Recommended in a cool and dark place, <15°C) |
包裝和容器 ![]() |
1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 6106-46-3 |
相關CAS RN ![]() |
13265-10-6 |
Reaxys-RN | 11258389 |
PubChem Substance ID | 87575767 |
Merck Index(14) | 8406 |
MDL編號 | MFCD00078239 |
產品規格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 195.0 to 199.0 °C |
Specific rotation [a]20/D | -23.0 to -27.0 deg(C=1, H2O) |
Solubility in Water | almost transparency |
性質
熔點 | 199 °C |
比旋光 [α]D | -25° (C=1,H2O) |
GHS
圖形表示 |
![]() |
信號詞 | Warning |
危險性說明 | H302 : Harmful if swallowed. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
RTECS # | YM3675150 |
運輸資料
UN編號 | UN1544 |
類別 | 6.1 |
包裝類別 | III |
HS編碼* | 2939.79-000 |
Application
Scopolamine Methyl Nitrate: A Belladonna Alkaloid with Anticholinergic Activity
Scopolamine salts ([S0021][ S0230] and [S0231]), belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)
References
- Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response
- Effects of cholinergic and monoaminergic antagonists and tranquilizers upon spatial memory in rats
- Scanning mutagenesis studies of the M1 muscarinic acetylcholine receptor
- High-pressure liquid chromatographic determination of methscopolamine nitrate, phenylpropanolamine hydrochloride, pyrilamine maleate, and pheniramine maleate in tablets
- Determination of phenylephrine hydrochloride, chlorpheniramine maleate, and methscopolamine nitrate in tablets or capsules by liquid chromatography with two UV absorbance detectors in series
考研文獻
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