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CAS RN: 155-41-9 | 產品號碼: S0231
Scopolamine Methyl Bromide
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| 產品號碼 | S0231 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__8H__2__4BrNO__4 = 398.30 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 155-41-9 |
| 相關CAS RN
|
13265-10-6 |
| Reaxys-RN | 4079680 |
| PubChem Substance ID | 87575768 |
| Merck Index(14) | 6003 |
| MDL編號 | MFCD00078560 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -23.0 to -26.0 deg(C=1, H2O) |
性質
| 比旋光 [α]D | -24° (C=1,H2O) |
GHS
相關法規
| RTECS # | YM3675000 |
運輸資料
| UN編號 | UN1544 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2939.79-000 |
Application
Scopolamine Methyl Bromide: A Belladonna Alkaloid with Anticholinergic Activity
Scopolamine salts ([S0021][S0230] and [S0231]), belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)
References
- Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response
- Effects of cholinergic and monoaminergic antagonists and tranquilizers upon spatial memory in rats
- Effects of physostigmine and scopolamine in rats' performances in object-recognition and radial-maze tests
- Scanning mutagenesis studies of the M1 muscarinic acetylcholine receptor
考研文獻
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