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CAS RN: 83-67-0 | 產品號碼: T0178
產品規格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
性質
| 熔點 | 350 °C |
| 溶解性（可溶於） | Solution of sodium hydroxide in water |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | XH2275000 |
運輸資料
| HS編碼* | 2939.79-000 |
Application
Efflux pump research
Theobromine has been reported to inhibit efflux pump in Gram-negative bacteria thereby having the synergy with ciprofloxacin [C2510] on antibacterial activity.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Natural and synthetic compounds such as trimethoprim behave as inhibitors of efflux in Gram-negative bacteria
- 1) Determination of theobromine, theophylline and caffeine in cocoa samples by a high-performance liquid chromatographic method with on-line sample cleanup in a switching-column system
- 2) Theobromine and the pharmacology of cocoa (a review)
- 3) Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice
- 4) Recent advances in caffeine and theobromine toxicities: a review
Application
Theobromine: A Bioactive Purine Alkaloid Contained in Coffee and Cocoa Based Foods
Theobromine, a purine alkaloid, is one of the abundant methylxanthine in coffee and cocoa based foods.1) Biological studies have been suggested that theobromine works as an adenosine receptor antagonist,2) and a phosphodiesterase (PDE) inhibitor to increase intracellular cyclic adenosine monophosphate (cAMP) [A2381].3) In addition, theobromine is a caffeine [C2042] metabolite which plays an important role in the biochemical processes of mammalian organisms.4) (The product is for research purpose only.)
References
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