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CAS RN: 136310-93-5 | 產品號碼: T3032
Tiotropium Bromide
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| 產品號碼 | T3032 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__9H__2__2BrNO__4S__2 = 472.41 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器
|
200MG-Glass Bottle with Plastic Insert （閲覽圖片）, 50MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 136310-93-5 |
| 相關CAS RN
|
186691-13-4 |
| Reaxys-RN | 11069044 |
| PubChem Substance ID | 253660050 |
| Merck Index(14) | 9454 |
| MDL編號 | MFCD00867027 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
| 熔點 | 230 °C |
| Maximum Wavelength | 240 nm |
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2934.99-000 |
Application
Tiotropium Bromide: A Potent Muscarinic Antagonist for M1-, M2- and M3-Receptors in Lung
Tiotropium bromide is an anticholinergic agent that antagonizes muscarinic M1-, M2- and M3-receptors in lung, and is approximately 10-fold more potent than ipratropium bromide [I0907].
References
- Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease
- Tiotropium bromide(a review)
- Preclinical evaluation of long-acting muscarinic antagonists: comparison of tiotropium and investigational drugs
- Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma
- Highly sensitive assay for tiotropium, a quaternary ammonium, in human plasma by high-performance liquid chromatography/tandem mass spectrometry
- A rapid, stability-indicating RP-HPLC method for the simultaneous determination of formoterol fumarate, tiotropium bromide, and ciclesonide in a pulmonary drug product
PubMed Literature
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