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CAS RN: 67-30-1 | 產品號碼: T3730
3,3',5,5'-Tetraiodothyroacetic Acid

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產品號碼 | T3730 |
純度/分析方法 ![]() |
>98.0%(HPLC)(N) |
分子式 / 分子量 | C__1__4H__8I__4O__4 = 747.83 |
外觀與形狀(20°C) | Solid |
儲存條件 ![]() |
Frozen (<0°C) |
應避免的情況 | Heat Sensitive |
包裝和容器 ![]() |
100MG-Glass Bottle with Plastic Insert (閲覽圖片), 500MG-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 67-30-1 |
Reaxys-RN | 2173215 |
PubChem Substance ID | 468592913 |
MDL編號 | MFCD00055932 |
產品規格
Appearance | White to Yellow to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
性質
熔點 | 230 °C |
GHS
圖形表示 |
![]() |
信號詞 | Danger |
危險性說明 | H300 : Fatal if swallowed. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
RTECS # | CY1585800 |
運輸資料
UN編號 | UN2811 |
類別 | 6.1 |
包裝類別 | I |
HS編碼* | 2918.99-000 |
Application
3,3',5,5'-Tetraiodothyroacetic Acid: A Thyroid Hormone Analogue with Anti-Angiogenesis and Anti-Tumor Growth Effects
3,3',5,5'-Tetraiodothyroacetic acid is a thyroid hormone (L-thyroxine [T0245]) analogue. It is reported that 3,3',5,5'-tetraiodothyroacetic acid acts at a cell surface receptor to block angiogenic and tumor cell proliferation action of thyroid hormones, which have been recently shown to induce tumor growth and angiogenesis. (The product is for research purpose only.)
References
- Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor
- Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid
- Metabolic Effects of Thyroid Hormone Derivatives (a review)
- Determination of levothyroxine and its degradation products in pharmaceutical tablets by HPLC-UV-ICP-MS
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