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CAS RN: 212142-18-2 | 產品號碼: V0198
Vatalanib Succinate
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| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 25MG |
NT$9,576
|
9 | 10 | 下單後約2週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | V0198 |
純度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__1__5ClN__4·C__4H__6O__4 = 464.91 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Frozen (-20°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 212142-18-2 |
| Reaxys-RN | 14123653 |
產品規格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
性質
GHS
相關法規
運輸資料
| HS編碼* | 2933.39-000 |
Application
Vatalanib Succinate: A Specific Inhibitor of VEGF Receptor Tyrosine Kinases
Vascular endothelial growth factor (VEGF) is one of the major factors involved in tumor angiogenesis and has become an important target for cancer therapy. Vatalanib succinate (PTK787 /ZK 222584) is a specific inhibitor of all three VEGF receptor (VEGF-R1, VEGF-R2 and VEGF-R3) tyrosine kinases, which shows antitumor and anti-angiogenic activity in cancer cells. (The product is for research use only.)
References
- PTK787 /ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
- Effects of PTK787 /ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model
- PTK787 /ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
- Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787 /ZK 222584 (a review)
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