Maintenance Notice (0:30 AM July 19 - 1:30 AM July 21, 2025 UTC): This website is scheduled to be unavailable due to maintenance. Maintenance may be completed earlier than scheduled. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Materials Science News July 2025 | [Product Highlights] Travoprost with Intra-Ocular-... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
请选择数量
CAS RN: 138046-43-2 | 產品號碼: Y0032
YM-750
×
![]()
×
| 包裝 | 價格 | 同一天 | 2-3个工作日 | 左側以上貨期 |
貨期資訊
|
|---|---|---|---|---|---|
| 20MG |
NT$5,754
|
30 | 0 | 下單後約2週內可以出貨 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
| 產品號碼 | Y0032 |
純度/分析方法 
|
>93.0%(HPLC)(qNMR) |
| 分子式 / 分子量 | C__3__1H__3__6N__2O = 452.64 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 138046-43-2 |
| Reaxys-RN | 8368179 |
| MDL編號 | MFCD00905424 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(qNMR) | min. 93.0 % |
| Melting point | 96.0 to 100.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 99 °C |
GHS
相關法規
運輸資料
| HS編碼* | 2924.29-000 |
Application
YM-750: A Potent and Selective Inhibitor of Acyl-Coenzyme A
Acyl-Coenzyme A (ACAT, also known as sterol O-acyltransferase or SOAT) is an intracellular enzyme that catalyzes the formation of cholesteryl esters from cholesterol and fatty acyl-CoA.1) Recently, many studies have suggested that ACAT-1 (SOAT-1) plays a critical role in cancer initiation and progression and is an attractive target for novel anticancer therapies.2) This product, YM-750, is a potent and selective inhibitor of ACAT.1,3,4) (The product is for research use only.)
References
- 1) Targeting Sterol O-Acyltransferase/Acyl-CoA:Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential (a review)
- 2) Cholesterol metabolism: New functions and therapeutic approaches in cancer (a review)
- 3) YM750, an ACAT Inhibitor, Acts on Adrenocortical Cells to Inhibit Aldosterone Secretion Due to Depolarization
- 4) Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）
SDS
請選擇語言。
請求的SDS不可用。
如需更多幫助，請聯繫我們 。
產品規格
檢驗報告(CoA)及其他文檔
請輸入批號
輸入的批號不正確
示例 CoA
可下載CoA示例。注：該示例可能非最新批次的CoA。
目前沒有該產品的 CoA 示例。
分析圖譜
請輸入批號
輸入的批號不正確
很抱歉，您搜索的分析圖譜無法提供。