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Stable Fluorinating Reagent with Ease of Handling (FLUOLEAD®)
4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride (FLUOLEAD®"), which was first reported by Umemoto, is a novel nucleophilic fluorinating reagent. Differing from other existing fluorinating reagents, such as DAST, FLUOLEAD is a crystalline solid with high thermal stability and less fuming character, which makes it easier to handle. FLUOLEAD®";" fluorinates a variety of substrates to afford the corresponding fluorinated compounds in good yields.
