Maintenance Notice (12:30 AM - 5:30 AM August 24, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Gelieve het aantal te selecteren
Bifunctional Silane
No.106(April 2002)
The silane 1 reacts with 3',5'-hydroxy groups of nucleoside in DMF in the presence of imidazole to yield cyclic silylene 2. This silylene 2 is not only a protected nucleoside, which spans the 3',5'-hydroxy groups of the sugar moiety, but also forms a trans-fused ring system similar to the biologically important cyclic nucleotides. For this reason, its utilization as a model compound of cyclic nucleotides is anticipated.
References
- 1)New sila-analogues of cyclic nucleotides
- 2)Peterson alkenation
- 3)Silaketals as tethers in intramolecular radical cyclizations
- 4)Synthesis of hexanucleotide analogues with diisopropylsilyl internucleotide linkages
The prices are subject to change without notice. Please confirm the newest price by our online catalog before placing an order.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.