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Published TCIMAIL newest issue No.198
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CAS RN: 16980-89-5 | Product Number: D4228
Bucladesine Sodium Salt
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Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Sodium Salt
- Dibutyryl cAMP Sodium Salt
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€88.00
|
1 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D4228 |
| Purity / Analysis Method | >95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__8H__2__3N__5NaO__8P = 491.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 16980-89-5 |
| Related CAS RN | 362-74-3 |
| PubChem Substance ID | 354335826 |
| Merck Index (14) | 1463 |
| MDL Number | MFCD00005843 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility (insoluble in) | Acetone, Ether |
GHS
Related Laws:
| EC Number | 241-059-4 |
| RTECS# | ES5055500 |
Transport Information:
| HS Number | 2934999090 |
Application
Bucladesine, A Cyclic Adenosine Monophosphate (cAMP) Agalogue
Bucladesine or Dibutyryl cAMP is a stabilized cyclic adenosine monophosphate (cAMP) [A2381, A2112] analogue. It is a cell-permeable, cyclic nucleotide derivative that mimics the action of cAMP. In addition, it is an inhibitor of cyclic nucleotide phosphodiesterase.
References
- Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
- Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP
- cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
- Up-regulation of monocytic IL-10 by tumor necrosis factor-α and cAMP elevating drugs
- Rat oocyte maturation in vitro: Relief of cyclic AMP inhibition by gonadotropins
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