Theophylline

Reference

• 1) Natural and synthetic compounds such as trimethoprim behave as inhibitors of efflux in Gram-negative bacteria
  • L.J.V. Piddock, M.I. Garvey, M.M. Rahman, S. Gibbons, J. Antimicrob. Chemother. 2010, 65, 1215.


应用
RNA aptamer research

Reference

• High-Resolution Molecular Discrimination by RNA
• R.D. Jenison, S.C. Gill, A. Pardi, B. Polisky, Science 1994, 263, 1425.


应用
Theophylline: A Bioactive Purine Alkaloid Contained in Tea and Cocoa
Theophylline is a purine alkaloid, is one of the abundant methylxanthine in tea (Camellia sinensis) and cocoa (Theobroma cacao).¹⁾ Biological studies have been suggested that theophylline works as an adenosine receptor antagonist,^2,3) and a phosphodiesterase (PDE) inhibitor to increase intracellular cyclic adenosine monophosphate (cAMP) [A2381].^2,3) Theophylline induces relaxation of smooth muscle of the bronchus, and used as a bronchodilator for the treatment of asthma and chronic obstructive pulmonary disease (COPD). (The product is for research purpose only.)

文献

• 1) Simultaneous HPLC Determination of Caffeine, Theobromine, and Theophylline in Food, Drinks, and Herbal Products
  • B. Srdjenovic, V. Djordjevic-Milic, N. Grujic, R. Injac, Z. Lepojevic, J. Chromatogr. Sci. 2008, 46, 144.
• 2) Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants (a review)
  • K. F. Rabe, H. Magnussen, G. Dent, Eur. Respir. J. 1995, 8, 637.
• 3) Theophylline (a review)
  • P. J. Barnes, Am. J. Respire. Crit. Care Med. 2013, 188, 901.


参考文献