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Published TCIMAIL newest issue No.201
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CAS RN: 66304-01-6 | Product Number: B3125
3H-1,2-Benzodithiol-3-one 1,1-Dioxide
Purity: >98.0%(HPLC)
Synonyms:
- Beaucage Reagent
Product Documents:
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| Product Number | B3125 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__7H__4O__3S__2 = 200.23 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 66304-01-6 |
| Reaxys Registry Number | 4180332 |
| PubChem Substance ID | 87560250 |
| SDBS (AIST Spectral DB) | 52141 |
| MDL Number | MFCD00132960 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 102.0 to 106.0 °C |
Properties (reference)
| Melting Point | 104 °C |
| Solubility (soluble in) | Toluene |
GHS
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
Sulfur-Transfer Reagents for Synthesis of Oligonucleotide Phosphorothioates

References
- Nucleic acid therapeutics: basic concepts and recent developments
- 3H-1,2-Benzodithiol-3-one 1,1-dioxide
- Phosphorothioate Oligonucleotides with Low Phosphate Diester Content: Greater than 99.9% Sulfurization Efficiency with “Aged” Solutions of Phenylacetyl Disulfide (PADS)
- Large-Scale Synthesis of Oligonucleotide Phosphorothioates Using 3-Amino-1,2,4-dithiazole-5-thione as an Efficient Sulfur-Transfer Reagent
- Mechanism of the sulfurisation of phosphines and phosphites using 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride)
Application
Beaucage Reagent

References
PubMed Literature
Documents
Product Articles
[TCIMAIL No.137] Beaucage Reagent[Product Highlights] Sulfur-Transfer Reagents for Synthesis of Oligonucleotide Phosphorothioates
Product Documents (Note: Some products will not have analytical charts available.)
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