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CAS RN: 160982-16-1 | Product Number: C2832
(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide
![Chemical Structure of (S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide](/medias/C2832.jpg?context=bWFzdGVyfHJvb3R8NTMzOTh8aW1hZ2UvanBlZ3xhREkwTDJnME1DODRPVEl3TnpZMU9ESTFNRFUwTDBNeU9ETXlMbXB3Wnd8Y2VjNjQyYWJlZjRkOGU0NzBmNmIxNzg4YTE1YjQ3ZDYwYjBlNDQ2YzdjOTcyOTYyZTczY2M4M2ZmODhjZjIxMg "(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide")
![Thumbnail of (S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide](/medias/C2832.jpg?context=bWFzdGVyfHJvb3R8MTYwMjR8aW1hZ2UvanBlZ3xhREEzTDJnME5pODRPVE0wTWpFME56azFNamswTDBNeU9ETXlMbXB3Wnd8NzQ4MjNlOWEyYWUzY2Q2NDhkZjFmMjdiZGM0NTEzZTU3M2Y2Y2E2MGM4NDNhZDQyOTVlYjNjZjI0ZWU4OTExNg)
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![(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide")
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹7,800.00
|
1 | 6 |
|
| 5G |
₹36,500.00
|
Contact Us | 7 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C2832 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__6ClNO__3S__2 = 239.69 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 160982-16-1 |
| Reaxys Registry Number | 13565602 |
| PubChem Substance ID | 253661636 |
| MDL Number | MFCD09033311 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 128.0 to 132.0 °C |
| Specific rotation [a]20/D | -4.0 to -6.0 deg(C=1, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 130 °C |
| Specific Rotation | -5° (C=1,MeOH) |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
Application
A Key Synthetic Intermediate of Brinzolamide
This product has been used as a key synthetic intermediate of brinzolamide [B4258] which is a specific carbonic anhydrase (CA) inhibitor specifically carbonic anhydrase II.
References
- Enantioselective Synthesis of Brinzolamide (AL-4862), a New Topical Carbonic Anhydrase Inhibitor. The "DCAT Route" to Thiophenesulfonamides
PubMed Literature
Documents
Product Articles
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Safety Data Sheet (SDS)
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Specifications
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