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CAS RN: 33564-30-6 | Product Number: C3602

Cefoxitin Sodium


Purity: >98.0%(T)(HPLC)
Synonyms:
  • Sodium (6R,7S)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Documents:
1G
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Product Number C3602
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__6N__3NaO__7S__2 = 449.43  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 33564-30-6
Reaxys Registry Number 4104290
Merck Index (14) 1936
MDL Number

MFCD00079042

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D +202 to +210 deg(C=1, MeOH)
Properties (reference)
Melting Point 204 °C
Specific Rotation 209° (C=1,MeOH)
Maximum Absorption Wavelength 260(H2O) nm
Solubility in water Completely soluble
Solubility (soluble in) Methanol
Solubility (very slightly) Ethanol,Acetone
Solubility (insoluble in) Aliphatic hydrocarbons
GHS
Related Laws:
RTECS# XI0330500
Transport Information:
Application
Cefoxitin Sodium: A Second Generation Cephem Antibiotic against beta-Lactamase

Cefoxitin sodium and its free acid [C3598] are semi-synthetic antibiotic that are derived from cephamycin C which is produced by Streptomyces lactamdurans. Cefoxitins have bactericidal activity against a wide range of Gram-negative and Gram-positive bacteria including aerobes and anaerobes.1,2) Cefoxitins are second generation cephem antibiotics which act by inhibition bacterial cell wall synthesis. Due to the presence of a 7-α methoxy group in the β-lactam ring, cefoxitins exhibit a high degree of stability in the presence of beta-lactamases.1,3)

References


Documents (Note: Some products will not have analytical charts available.)
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