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CAS RN: 56238-63-2 | Product Number: C3747

Cefuroxime Sodium


Purity: >97.0%(T)(HPLC)
Synonyms:
  • Sodium (6R,7R)-3-[(Carbamoyloxy)methyl]-7-[2-(2-furyl)(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
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Product Number C3747
Purity / Analysis Method >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__5N__4NaO__8S = 446.37 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 56238-63-2
Reaxys Registry Number 6560595
PubChem Substance ID 468591254
MDL Number

MFCD09878727

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Volumetric Analysis) min. 97.0 %
Specific rotation +56.0 ~ +62.0 deg (C=1, Water)
Water max. 3.0 %
NMR confirm to structure
Properties (reference)
Melting Point 186 °C(dec.)
GHS
Related Laws:
RTECS# XI0330000
Transport Information:
Application
Cefuroxime Sodium: A Second Generation Cephalosporin with Increased Stability to β-Lactamase

Cefuroxime (sodium) is a second generation semisynthetic cephalosporin known to interfere with the final stages of peptidoglycan synthesis in bacterial cell wall. Cefuroxime has a broad bactericidal activity against both Gram-positive and Gram-negative organisms. Cefuroxime has a methoxyimino group in the 7-position side chain. The methoxyimino group give cefuroxime stability against β-lactamase and enhances the antibacterial activity against Gram-negative organisms. For your reference, cefuroxime axetil is an ester prodrug which permits the oral administration of cefuroxime. (The product is for research purpose only.)

References


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