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CAS RN: 105628-07-7 | Product Number: F0839

Fasudil Hydrochloride


Purity: >98.0%(HPLC)
Synonyms:
  • 1-(5-Isoquinolinesulfonyl)homopiperazine Hydrochloride
  • 5-(1-Homopiperazinyl)sulfonylisoquinoline Hydrochloride
Documents:
100MG
₹7,800
2   3  

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Product Number F0839
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__1__7N__3O__2S·HCl = 327.83 
Physical State (20 deg.C) Solid
CAS RN 105628-07-7
Related CAS RN 186694-02-0&103745-39-7
Reaxys Registry Number 5466340
PubChem Substance ID 160871255
Merck Index (14) 3942
MDL Number

MFCD00943198

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 12.0 to 13.5 %
Properties (reference)
Melting Point 222 °C(dec.)
Solubility in water Soluble
Solubility (soluble in) Methanol
Solubility (very slightly) Ethanol
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# HM4033500
Transport Information:
Application
Protein Kinase Inhibitor

References


Application
Fasudil Hydrochloride: A Rho Kinase Inhibitor

Fasudil hydrochloride (HA-1077) is a prodrug of hydroxyfasudil [H1745 (HCl salt)], which is a potent and selective Rho kinase (a protein phosphatase) inhibitor. Hydroxyfasudil inhibits phosphorylation of myosin light chain, the final step in the vascular smooth muscle contractile mechanism, by inhibiting Rho kinase. Fasudil has been used as a vasodilator for the treatment of cerebral vasospasm. (The product is for research purpose only.)

References


PubMed Literature


Documents (Note: Some products will not have analytical charts available.)
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