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CAS RN: 152459-95-5 | Product Number: I0906

Imatinib


Purity: >98.0%(HPLC)
Synonyms:
Documents:
100MG
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1G
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Product Number I0906
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__9H__3__1N__7O = 493.62 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (<0°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 152459-95-5
Related CAS RN 220127-57-1
Reaxys Registry Number 9300263
PubChem Substance ID 253661909
Merck Index (14) 4902
MDL Number

MFCD05662257

Specifications
Appearance White to Light yellow to Light orange powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Melting point 207.0 to 211.0 °C
Properties (reference)
Melting Point 209 °C
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# CV5585673
Transport Information:
Application
Imatinib: A Tyrosine Kinase Inhibitor and a Molecular-Targeted Agent

Imatinib is a synthetic tyrosine (Tyr) kinase inhibitor and a molecular-targeted agent that specifically target several protein tyrosine kinases, such as stem-cell factor receptor (c-KIT), platelet-derived growth factor receptor (PDGF-R), and notably Bcr-Abl. Imatinib mesylate [I0936] is used in the treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. (The product is for research purpose only.)

References


PubMed Literature


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Other Documents

Life Science
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