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CAS RN: 103577-40-8 | Product Number: M2800
Lansoprazole Sulfide
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridylmethylthio]benzimidazole
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹5,800.00
|
3 | 6 |
|
| 5G |
₹13,200.00
|
3 | ≥40 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | M2800 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4F__3N__3OS = 353.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 103577-40-8 |
| Reaxys Registry Number | 4331839 |
| PubChem Substance ID | 354334217 |
| MDL Number | MFCD00834357 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 147.0 to 151.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 149 °C |
| Maximum Absorption Wavelength | 292 nm (EtOH) |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Application
ランソプラゾールの合成中間体および代謝生成物，ランソプラゾールスルフィド
Lansoprazole sulfide is a synthetic intermediate1,2) and a metabolite of lansoprazole [L0233].3,4) In 2010s, asymmetric oxidation of lansoprazole sulfide has been reported. 5,6)
References
- 1)Synthesis of 2-[[(4-Fluoroalkoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazoles as Antiulcer Agents
- 2)An Improved Process for the Production of Lansoprazole: Investigation of Key Parameters That Influence the Water Content in Final API
- 3)Identification of the human P450 enzymes involved in lansoprazole metabolism
- 4)Determination of lansoprazole and five metabolites in plasma by high-performance liquid chromatography
- 5)Davis Oxaziridine-Mediated Asymmetric Synthesis of Proton Pump Inhibitors Using DBU Salt of Prochiral Sulfide
- 6)Isoinversion Behavior in the Enantioselective Oxidations of Pyridylmethylthiobenzimidazoles to Chiral Proton Pump Inhibitors on Titanium Salalen Complexes
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