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CAS RN: 1485-00-3 | Product Number: M3390

MNS


Purity: >98.0%(GC)
Synonyms:
  • 3,4-Methylenedioxy-β-nitrostyrene
  • 5-(2-Nitrovinyl)-1,3-benzodioxole
  • 5-(2-nitrovinyl)benzo[d][1,3]dioxole
  • MDBN
Documents:
100MG
₹6,600.00
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500MG
₹16,000.00
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Product Number M3390
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__9H__7NO__4 = 193.16 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (-20°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive,Heat Sensitive
CAS RN 1485-00-3
Reaxys Registry Number 15499
PubChem Substance ID 468592438
MDL Number

MFCD00014575

Specifications
Appearance Light yellow to Yellow to Green powder to crystal
Purity(GC) min. 98.0 %
Melting point 159.0 to 163.0 °C
NMR confirm to structure
Properties (reference)
Melting Point 161 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
RTECS# WL5270000
Transport Information:
Application
MNS: A Potent Antiplatelet Agent with Tyrosine Kinase Inhibitory Activity, and a NLRP3 Inflammasome Inhibitor

MNS, the β-nitrostyrene derivative, is a potent antiplatelet agent with tyrosine kinase inhibitory activity.1,2) It has recently been reported that NLR family pyrin domain-containing protein 3 (NLRP3), a pattern recognition receptor, forms a complex called NLRP3 inflammasome in response to irritating metabolites and pathogens, and induces the production of pro-inflammatory cytokines, Interleukin (IL)-1β and IL-18. MNS has also attracted attention as a NLRP3 inflammasome inhibitor which shows anti-inflammatory activity.3,4) (The product is for research purpose only.)

References

Articles/Brochures

Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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