Published TCIMAIL newest issue No.192 | [Product Highlights] DOTA Derivatives as Chelating Agents for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 1445-07-4 | Product Number: P2939
Pseudouridine (Synthetic)
Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- 5-(β-D-Ribofuranosyl)uracil (Synthetic)
- 5-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione (Synthetic)
- (1S)-1,4-Anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-ribitol (Synthetic)
- ψ (Synthetic)
Documents:
Size | Unit Price | Hyderabad | Japan* | Quantity |
---|---|---|---|---|
100MG |
₹14,300.00
|
Contact Us | 10 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | P2939 |
Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
Molecular Formula / Molecular Weight | C__9H__1__2N__2O__6 = 244.20 |
Physical State (20 deg.C) | Solid |
Storage Temperature | <0°C |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
CAS RN | 1445-07-4 |
Reaxys Registry Number | 621385 |
MDL Number | MFCD00038458 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(qNMR) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 231 °C |
GHS
Related Laws:
Transport Information:
Application
Pseudouridine (Ψ): A Modified Pyrimidine Nucleoside Found in RNA
In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune, making it a viable new platform for vaccine development.1) Additionally there are reports on incorporation of modified nucleobases into mRNA offering advantages for the generation of potent and long-lived antibody responses.2) In protein biosynthesis, pseudouridines, such as pseudouridine (Ψ) [P2939 (synthetic)] [P2396] and 1-methylpseudouridine (m1Ψ) [M3387], are read like uridine (U) and enable comparatively high protein yields.3) Furthermore, pseudouridine has attracted attention for its function in epitranscriptomics, namely the study of RNA modifications.2,4)
References
- 1) The tangled history of mRNA vaccines (a review)
- 2) Chemical Modifications to RNA: A New Layer of Gene Expression Regulation (a review)
- 3) Messenger RNA modifications: Form, distribution, and function (a review)
- 4) Epitranscriptome sequencing technologies: decoding RNA modifications
PubMed Literature
Please visit the Pubchem page at this link.
Articles/Brochures
TCIMAIL
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.