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CAS RN: 1508-75-4 | Product Number: T1470

Tropicamide

Purity: >99.0%(T)(HPLC)

Synonyms:

N-Ethyl-N-(4-pyridylmethyl)tropamide

Documents:

SDS | Specifications | C of A & Other Certificates | Analytical Charts

Size	Unit Price	Hyderabad	Japan*	Quantity
10G	₹7,400.00	2	28

*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

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General Information plus

Product Number	T1470
Purity / Analysis Method	>99.0%(T)(HPLC)
Molecular Formula / Molecular Weight	C__1__7H__2__0N__2O__2 = 284.36
Physical State (20 deg.C)	Solid
Storage Temperature	Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN	1508-75-4
Reaxys Registry Number	285563
PubChem Substance ID	87577232
Merck Index (14)	9780
MDL Number	MFCD00058580

Specifications & Properties plus

Specifications

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 99.0 area%
Purity(Nonaqueous Titration)	min. 99.0 %
Melting point	97.0 to 100.0 °C
NMR	confirm to structure

Properties (reference)

Melting Point	98 °C
Maximum Absorption Wavelength	254(HCl aq.) nm
Solubility (soluble in)	Chloroform, Ethanol

Safety & Regulations plus

GHS

Pictogram
Signal Word	Warning
Hazard Statements	H302 : Harmful if swallowed.
Precautionary Statements	P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.

Related Laws:

RTECS#

CY1487860

Transport Information:

Applications plus

Application

Tropicamide: A Muscarinic M4 Receptor Antagonist

Tropicamide is a muscarinic M₄ receptor antagonist. Tropicamide produces short acting cycloplegia and mydriasis when applied as eye drops. Tropicamide has an action similar to atropine [A0754], but its cycloplegic and mydriatic effects have a more rapid onset and a shorter duration of effect. Tropicamide is slightly soluble in water and in diethyl ether, freely soluble in ethanol and in chloroform. (The product is for research purpose only.)

References

The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M₄ receptors
- A. J. Betz, P. J. McLaughlin, M. Burgos, S. M. Weber, J. D. Salamone, Psychopharmacology 2007, 194, 347.
The modulation of fragile X behaviors by the muscarinic M₄ antagonist, tropicamide
- S. Veeraragavan, N. Bui, J. R. Perkins, L. A. Yuva-Paylor, R. Paylor, Behav. Neurosci. 2011, 125, 783.
Preparation and evaluation of liposomal formulations of tropicamide for ocular delivery
- M. S. Nagarsenker, V. Y. Londhe, G. D. Nadkarni, Int. J. Pharm. 1999, 190, 63.
Tropicamide (a review on the physical properties, synthesis, stability, metabolism and analysis)
- K. W. Blessel, B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subst. 1974, 3, 565.
High-performance liquid chromatographic determination of phenylephrine and tropicamide in human aqueous humor
- M. J. Galmier, A. M. Frasey, S. Meski, E. Beyssac, J. Petit, J. M. Aiache, C. Lartigue, Biomed. Chromatogr. 2000, 14, 202.

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CAS RN: 1508-75-4 | Product Number: T1470