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CAS RN: 64-75-5 | Product Number: T2525

Tetracycline Hydrochloride

Purity: >98.0%(T)
Contact Us ≥40 
Contact Us ≥40 

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Product Number T2525
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__2__2H__2__4N__2O__8·HCl = 480.90 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 64-75-5
Related CAS RN 60-54-8
Reaxys Registry Number 3844873
PubChem Substance ID 87560362
Merck Index (14) 9196
MDL Number


Appearance Light yellow to Amber to Dark green powder to crystal
Purity(HPLC) min. 95.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -240 to -255 deg(C=0.5, 0.1mol/L HCl)
Properties (reference)
Melting Point 214 °C(dec.)
Specific Rotation -253° (C=0.5,0.1mol/L HCl)
Solubility in water Soluble
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# QI9100000
Transport Information:
Tetracycline: a Broad Spectrum Polyketide Antibiotic and a Selective Reagent Genetically Engineered Cells

Tetracycline is a polyketide antibiotic isolated from Streptomyces genus. Tetracycline has broad activity against Gram-negative bacteria and Gram-positive bacteria, with a few exceptions, such as Pseudomonas aeruginosa and Proteus species. Tetracycline inhibits protein synthesis in susceptible organisms by binding to the A-site on the 50S subunit of a bacterial ribosome. However, tetracycline-resistant bacterial strains appeared soon after its introduction. Tetracycline is used in molecular biology as a selective reagent most commonly to isolate bacteria coupled to a gene coding for tetracycline resistance, which is one of the most frequently used selection markers for obtaining transgenic cells. Recently, tetracycline is used for tetracycline-controlled transcriptional activation systems in cells.


PubMed Literature

Documents (Note: Some products will not have analytical charts available.)
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