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CAS RN: 33005-95-7 | Product Number: T3175
Tiaprofenic Acid
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Purity: >98.0%(GC)(T)
Synonyms:
- 2-(5-Benzoylthiophen-2-yl)propionic Acid
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
₹3,500.00
|
1 | 7 |
|
| 100MG |
₹7,800.00
|
Contact Us | 13 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T3175 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__4H__1__2O__3S = 260.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 33005-95-7 |
| Reaxys Registry Number | 1380662 |
| PubChem Substance ID | 253660472 |
| Merck Index (14) | 9422 |
| MDL Number | MFCD00866089 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 96.0 to 100.0 °C |
Properties (reference)
| Melting Point | 99 °C |
| Maximum Absorption Wavelength | 314 nm (Phosphate buffer sol.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | XM7580000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
Application
Tiaprofenic acid: A NSAID of the 2-Arylpropionic Acid Class.
Tiaprofenic acid is a nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid (2-APA) class. The S-enantiomer possessing most of the beneficial anti-inflammatory activity. Tiaprofenic acid and the other 2-APAs (eg: carprofen [C2701], naproxen [M1021] and ketoprofen [K0038]) have been reported their photosensitizing side effects caused by their photodegradation products.
References
- 1)Tiaprofenic acid: A reappraisal of its pharmacological properties and use in the management of rheumatic diseases
- 2)Clinical pharmacokinetics of tiaprofenic acid and its enantiomers
- 3)Photoreactivity of the nonsteroidal anti-inflammatory 2-arylpropionic acids with photosensitizing side effects (a review)
- 4)Tiaprofenic acid-photosensitized damage to nucleic acids: a mechanistic study using complementary in vitro approaches
- 5)High-performance liquid chromatographic assay of ketoprofen enantiomers in human plasma and urine
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