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CAS RN: 133550-37-5 | Product Number: T3540
Tyrphostin AG 835
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Purity: >98.0%(HPLC)
Synonyms:
- (S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
- (S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
₹6,000.00
|
Contact Us | 8 |
|
| 100MG |
₹12,800.00
|
Contact Us | 32 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T3540 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__1__6N__2O__3 = 308.34 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 133550-37-5 |
| Reaxys Registry Number | 4356230 |
| PubChem Substance ID | 354334648 |
| MDL Number | MFCD00209855 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Specific rotation [a]20/D | +93.0 to +98.0 deg(C=0.5,MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 146 °C |
| Specific Rotation | 96° (C=0.5,MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P405 : Store locked up. |
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Application
Tyrphostin AG 835 (Tyrphostin B44): A Potent Inhibitor of Epidermal Growth Factor Receptor (EGFR) Kinase
Tyrphostin AG 835 (tyrphostin B44) is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase.
References
- Tyrphostins. II. Heterocyclic and α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases
PubMed Literature
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Specifications
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