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CAS RN: 60-54-8 | Product Number: T3971

Tetracycline


Purity: >95.0%(T)(HPLC)
Synonyms:
  • (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
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Product Number T3971
Purity / Analysis Method >95.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__4N__2O__8 = 444.44 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive,Heat Sensitive
CAS RN 60-54-8
Reaxys Registry Number 2230417
PubChem Substance ID 468593045
Merck Index (14) 9196
MDL Number

MFCD00151232

Specifications
Appearance Light yellow to Yellow powder to crystal
Purity(HPLC) min. 95.0 area%
Purity(Volumetric Analysis) min. 95.0 %(calcd. on anh. substance)
Water max. 5.0 %
Properties (reference)
Melting Point 164 °C(dec.)
Maximum Absorption Wavelength 357(H2O) nm
Solubility in water Insoluble
Degree of solubility in water 231 mg/l   25 °C
Solubility (slightly sol. in) Alcohol
Solubility (insoluble in) Ether,Chloroform
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# QI8750000
Transport Information:
Application
Tetracycline: a Broad Spectrum Polyketide Antibiotic and a Selective Reagent Genetically Engineered Cells

Tetracycline is a polyketide antibiotic isolated from Streptomyces genus. Tetracycline has broad activity against Gram-negative bacteria and Gram-positive bacteria, with a few exceptions, such as Pseudomonas aeruginosa and Proteus species. Tetracycline inhibits protein synthesis in susceptible organisms by binding to the A-site on the 50S subunit of a bacterial ribosome. However, tetracycline-resistant bacterial strains appeared soon after its introduction. Tetracycline is used in molecular biology as a selective reagent most commonly to isolate bacteria coupled to a gene coding for tetracycline resistance, which is one of the most frequently used selection markers for obtaining transgenic cells. Recently, tetracycline is used for tetracycline-controlled transcriptional activation systems in cells. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
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