It has come to our notice that certain fraudulent individuals or entities are misusing our Company’s name and TCI’s registered trademarks by promoting and offering regulated and hazardous chemical substances through online platforms like YouTube. We hereby categorically clarify that TCI has no association or connection whatsoever with the products being displayed or sold in the videos. These products have been falsely represented as being associated with TCI, and the unauthorized use of our trademark and brand name is both illegal and misleading. TCI Chemicals markets and sells its products exclusively through its official website and authorized distributors. If you become aware of any such fraudulent activity or require clarification, you may reach out to us at: Sales-IN@TCIchemicals.com. Click Here to View the Caution Notice.
Product Document Searching Made Easy by 2D Code! | [Product Highlights] Endogenous Biotin-Blocking Reagent...Maximum quantity allowed is 999
Please select the quantity
CAS RN: 71369-59-0 | Product Number: T4139
(-)-Talinolol
×
![]()
×
Purity: >95.0%(T)(HPLC)
Synonyms:
- (S)-1-[4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea
- 1-[4-[(2S)-3-(tert-Butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 20MG |
₹11,700.00
|
Contact Us | 33 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T4139 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__3N__3O__3 = 363.50 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 71369-59-0 |
| Related CAS RN | 57460-41-0 |
| Reaxys Registry Number | 8353028 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Melting point | 142.0 to 146.0 °C |
| Specific rotation | -9.0 to -11.0 deg(C=0.1, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 144 °C |
GHS
Related Laws:
Transport Information:
Application
(-)-Talinolol: A Model Compound for P-Glycoprotein Drug-Drug Interaction Studies
(±)-Talinolol, a β1-selective adrenoceptor antagonist, has been used as a suitable model compound for P-glycoprotein drug-drug interaction studies due to its P-glycoprotein-related active intestinal secretion and lack of any significant metabolism.1,2) (-)-Talinolol is the active (S)-isomer as a β1-selective adrenoceptor antagonist, and can also be used as a model compound for the studies.3,4) (The product is for research purpose only.)
References
- 1) Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction
- 2) P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans
- 3) Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: concentration- and dose-dependent absorption in vitro and in vivo
- 4) Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.