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CAS RN: 15421-84-8 | Product Number: T4243

Trapidil

Purity: >98.0%(HPLC)(qNMR)

Synonyms:

N,N-Diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Documents:

SDS | Specifications | C of A & Other Certificates | Analytical Charts

Size	Unit Price	Hyderabad	Japan*	Quantity
10MG	₹5,500.00	Contact Us	10
50MG	₹19,800.00	Contact Us	10

*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

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General Information plus

Product Number	T4243
Purity / Analysis Method	>98.0%(HPLC)(qNMR)
Molecular Formula / Molecular Weight	C__1__0H__1__5N__5 = 205.27
Physical State (20 deg.C)	Solid
Storage Temperature	Refrigerated (0-10°C)
Store Under Inert Gas	Store under inert gas
Condition to Avoid	Air Sensitive,Heat Sensitive
CAS RN	15421-84-8
Reaxys Registry Number	186842
MDL Number	MFCD00193104

Specifications & Properties plus

Specifications

Appearance	White to Light yellow powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(qNMR)	min. 98.0 %
Melting point	100.0 to 104.0 °C
NMR	confirm to structure

Properties (reference)

Melting Point	102 °C
Solubility (slightly sol. in)	Diethyl ether

Safety & Regulations plus

GHS

Pictogram
Signal Word	Danger
Hazard Statements	H301 : Toxic if swallowed.
Precautionary Statements	P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up.

Related Laws:

RTECS#

XZ5700000

Transport Information:

UN Number	UN2811
Class	6.1
Packing Group	III

Applications plus

Application

Trapidil: A Platelet-Derived Growth Factor (PDGF) Antagonist

Trapidil was originally developed as an antiplatelet agent and vasodilator.^1,2) Subsequently, trapidil has been reported as a platelet-derived growth factor (PDGF) antagonist with anti-proliferative effects.^3,4) (The product is for research use only.)

References

1) Effect of trapidil on prostacyclin generation of arterial wall
- T. Kawamura, T. Kitani, Y. Okajima, O. Okuda, S. Urano, M. Watada, M. Nakagawa, H. Ijichi, Prostaglandins Med. 1980, 5, 113.
2) Antithrombotic activity and the mechanism of action of trapidil (Rocornal^®)
- Y. Suzuki, K. Yamaguchi, S. Shimada, Y. Kitamura, H. Ohnishi, Prostaglandins Leukot. Med. 1982, 9, 685.
3) Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro
- J.-i. Kuratsu, Y. Ushio, J Neurosurg. 1990, 73, 436.
4) Trapidil Inhibits Platelet-Derived Growth Factor–Stimulated Mitogen-Activated Protein Kinase Cascade
- M. Hoshiya, M. Awazu, Hypertension 1998, 31, 665.

Documents (Note: Some products will not have analytical charts available.)

Safety Data Sheet (SDS)

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CAS RN: 15421-84-8 | Product Number: T4243