“Due to maintenance activity, our telephone lines "22620909/1800 425 7889" will not be available from 8 to 19th August, we kindly request you to reach us via
email: Sales-in@tcichemicals.com or through Live Chat for your queries.”
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 181695-72-7 | Product Number: V0133
Valdecoxib
×
![]()
×
Purity: >98.0%(HPLC)(N)
Synonyms:
- 4-(5-Methyl-3-phenyl-4-isooxazolyl)benzenesulfonamide
Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
₹4,700
|
2 | Contact Us |
|
| 1G |
₹15,200
|
3 | 12 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | V0133 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__3S = 314.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | 0-10°C |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 181695-72-7 |
| Reaxys Registry Number | 8563786 |
| Merck Index (14) | 9900 |
| MDL Number | MFCD00950568 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 169.0 to 173.0 °C |
Properties (reference)
| Melting Point | 170 °C |
| Maximum Absorption Wavelength | 202(H2O) nm |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Ethanol,Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H373 : May cause damage to organs through prolonged or repeated exposure. H411 : Toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P391 : Collect spillage. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | DB2944030 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
Application
Valdecoxib: A Selective Cyclo-Oxygenase-2 (COX-2) Inhibitor
Valdecoxib (SC 65872), a non-steroidal anti-inflammatory drug (NSAID), is a selective cyclo-oxygenase-2 (COX-2) inhibitor. In theory, a drug such as valdecoxib that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1.
References
- 1. 4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2
- Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity
- Selective cyclooxygenase-2 inhibitors: similarities and differences (a review)
- Progress in COX-2 inhibitors: a journey so far (a review)
- Pharmacokinetics and metabolism of a COX-2 inhibitor, valdecoxib, in mice
- Determination of valdecoxib and its metabolites in human urine by automated solid-phase extraction-liquid chromatography-tandem mass spectrometry
Articles/Brochures
TCIMAIL
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number
Incorrect Lot Number is entered
The requested analytical chart is not available. Sorry for the inconvenience.