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CAS RN: 107753-78-6 | Product Number: Z0029

Zafirlukast


Purity: >98.0%(HPLC)
Synonyms:
  • Cyclopentyl N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamate
  • N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester
  • Cyclopentyl [3-[2-Methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methyl-1H-indol-5-yl]carbamate
  • [3-[2-Methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester
Documents:
100MG
₹10,300
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Product Number Z0029
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__3__1H__3__3N__3O__6S = 575.68  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive
CAS RN 107753-78-6
Reaxys Registry Number 3641829
PubChem Substance ID 253661584
Merck Index (14) 10108
MDL Number

MFCD00864775

Specifications
Appearance White to Gray to Brown powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 95.0 %
Properties (reference)
Solubility in water Insoluble
Solubility (soluble in) Dimethylformamide
Solubility (slightly sol. in) Acetone
Solubility (insoluble in) Toluene,Methanol
GHS
Related Laws:
RTECS# FB3966200
Transport Information:
Application
Zafirlukast: A Competitive and Selective Peptide Leukotriene Receptor Antagonist

Zafirlukast is a competitive and selective peptide leukotriene receptor antagonist. It binds to the CysLT1 receptors competitively with these cysteinyl leukotrienes (LTC4,LTD4 and LTE4). On the other hand, zafirlukast metabolism by cytochrome P450 3A4 (CYP3A4) has been reported.

References


PubMed Literature


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