Recently, Shiina et al. have been reported a new condensation method using dehydrating condensing agents 1 and 2. In the presence of 1 or 2, carboxylic acids react with nearly equimolar amounts of alcohols or amines to obtain corresponding carboxylic esters or amides in high yields.
1 and 2 perform effectively under Lewis acidic conditions and basic conditions, respectively. Therefore, a wide variety of substrates can be used by choosing 1 and 2.
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