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CAS RN: 3056-17-5 | Product Number: D3580
2',3'-Didehydro-3'-deoxythymidine
Purity: >98.0%(T)(HPLC)
Synonyms:
- d4T
- 2',3'-Anhydrothymidine
- 1-(2,3-Dideoxy-β-D-glycero-2-pentenofuranosyl)thymine
- Stavudine
- Sanilvudine
Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH | Shipping Information |
---|---|---|---|---|---|
1G |
¥6,600
|
3 | 8 | Contact Us | |
5G |
¥21,000
|
17 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Note:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
Product Number | D3580 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__0H__1__2N__2O__4 = 224.22 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 3056-17-5 |
Reaxys Registry Number | 618327 |
PubChem Substance ID | 87559878 |
SDBS (AIST Spectral DB) | 52178 |
MDL Number | MFCD00132921 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Specific rotation [a]20/D | -44.0 to -48.0 deg(C=0.69, H2O) |
NMR | confirm to structure |
Properties (reference)
Melting Point | 166 °C(dec.) |
Specific Rotation | -46° (C=0.69,H2O) |
Solubility in water | Soluble |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H373 : May cause damage to organs through prolonged or repeated exposure. H341 : Suspected of causing genetic defects. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | XP2075000 |
Transport Information:
Application
Stavudine: A Nucleoside Reverse Transcriptase Inhibitor
Stavudine is a nucleoside reverse transcriptase inhibitor that active against HIV1. Stavudine is a synthetic nucleoside analogue of the naturally occurring nucleoside thymidine. Intracellularly, stavudine is converted by cellular enzymes to the active metabolite, stavudine-5'-triphosphate. The triphosphate inhibits the activity of viral reverse transcriptase both by competing with the natural substrate, thymidine-5'-triphosphate, and by its incorporation into viral DNA causing termination of viral DNA chain. (The product is for research purpose only.)
References
- Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus
- Antiretroviral activity of stavudine (2',3'-didehydro-3'-deoxythymidine, D4T) (a review)
- Comparison of metabolism and in vitro antiviral activity of stavudine versus other 2',3'-dideoxynucleoside analogues
Application
Synthesis and Anti-HIV-1 Activities of Novel Podophyllotoxin Derivatives Containing Stavudine
References
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