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CAS RN: 51-21-8 | Product Number: F0151

5-Fluorouracil


Purity: >99.0%(T)(HPLC)
Chemical Substance Law (ENCS):   9-1180
Synonyms:
  • 5-FU
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Product Number F0151
Purity / Analysis Method >99.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__4H__3FN__2O__2 = 130.08  
Physical State (20 deg.C) Solid
CAS RN 51-21-8
Reaxys Registry Number 127172
PubChem Substance ID 87569939
SDBS (AIST Spectral DB) 3722
Merck Index (14) 4181
MDL Number

MFCD00006018

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 99.0 area%
Purity(Neutralization titration) min. 99.0 %
Solubility in hot Water almost transparency
Properties (reference)
Melting Point 283 °C(dec.)
Solubility in water Slightly soluble
Solubility (soluble in) Dimethylformamide
Solubility (slightly sol. in) Methanol
Solubility (very slightly) Ethanol
Solubility (insoluble in) Ether,Chloroform,Benzene
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
Chemical Substance Law (ENCS) 9-1180
RTECS# YR0350000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
Application
5-Fluorouracil (5-FU): An Antitumor Antimetabolite with Activity against Numerous Types of Neoplasms

5-Fluorouracil (5-FU) is an antitumor antimetabolite with activity against numerous types of neoplasms. Further, many prodrugs of 5-FU have been developed to increased plasma and tumor 5-FU concentrations and to improve the cytotoxicity, such as capecitabine [C2878], doxifluridine [D3579], carmofur [C2663], tegaful [F0635], UFT (tegafur and uracil [U0013]) and S-1 (tegafur, gimeracil [C2243] and potassium oxonate [O0164]). (The product is for research purpose only.)

References


Application
Reagent for gastropathy (gastric mucosal injury) model

References


Application
Reagent for nausea or vomiting model

Reference


PubMed Literature


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