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CAS RN: 920-66-1 | Product Number: H0424
1,1,1,3,3,3-Hexafluoropropan-2-ol
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Purity: >99.0%(GC)
Chemical Substance Law (ENCS):
2-291
Synonyms:
- 1,1,1,3,3,3-Hexafluoro-2-propanol
- 1,1,1,3,3,3-Hexafluoroisopropyl Alcohol
- HFP
- HFIP
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 25G |
¥7,400
|
≥80 | ≥60 | ≥100 | |
| 100G |
¥18,600
|
≥100 | ≥60 | ≥100 | |
| 500G |
¥73,500
|
≥60 | ≥40 | ≥100 |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | H0424 |
Purity / Analysis Method 
|
>99.0%(GC) |
| Molecular Formula / Molecular Weight | C__3H__2F__6O = 168.04 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 920-66-1 |
| Reaxys Registry Number | 1841007 |
| PubChem Substance ID | 87570824 |
| SDBS (AIST Spectral DB) | 5259 |
| MDL Number | MFCD00011651 |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 99.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | -4 °C |
| Boiling Point | 58 °C |
| Specific Gravity (20/20) | 1.62 |
| Refractive Index | 1.28 |
| Maximum Absorption Wavelength | 229 nm |
| Solubility in water | Soluble |
| Solubility (soluble in) | Ether, Acetone |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 + H332 : Harmful if swallowed or if inhaled. H314 : Causes severe skin burns and eye damage. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
| Chemical Substance Law (ENCS) |
2-291 |
| RTECS# | UB6450000 |
Transport Information:
| UN Number | UN1760 |
| Class | 8 |
| Packing Group | III |
Application
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP): A Solvent with Specific Properties
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP) is used as a solvent with specific properties. Its combination of high H bonding donor ability, low nucleophilicity, and high ionizing power allows reactions to proceed under mild conditions, which usually require the use of added reagents or metal catalysts to be carried out. In addition, HFIP is used as acid in volatile buffers for ion pair HPLC.
References
- Fluorinated alcohols: A new medium for selective and clean reaction (a review)
- 1,1,1,3,3,3-Hexafluoro-2-propanol (a review of the properties, handling and applications)
- 1,1,1,3,3,3-Hexafluoro-2-propanol for the removal of the 4,4'-dimethoxytrityl protecting group from the 5'-hydroxyl of acid-sensitive nucleosides and nucleotides
- New TFA-Free Cleavage and Final Deprotection in Fmoc Solid-Phase Peptide Synthesis: Dilute HCl in Fluoro Alcohol
- Making radical cations live longer
- Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry
PubMed Literature
Documents
Product Articles
[Product Highlights] Synthesis of N-H Aziridines from Unactivated Olefins Using Hydroxylamine-O-Sulfonic AcidProduct Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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Analytical Charts
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Other Documents
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1,1,1,3,3,3-Hexafluoropropan-2-ol [for HPLC]
| Product # | H1793 |
| CAS RN | 920-66-1 |
| Purity / Analysis Method: | >99.5%(GC) |